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Center for Astrophysics Research and Technologies Seminar Series Information

 

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Next-generation optical imaging methods for probing the nervous system

Thursday February 20, 2020
11:30 am


 Presenter:  Dr. Cristina Rodríguez, University of California, Berkeley
 Series:  OSE Seminars
 Abstract:  Optical microscopy has allowed the discovery of physical structures and phenomena otherwise invisible or unresolvable to our bare eyes. In particular, nonlinear optical microscopy has revolutionized our ability to image inside scattering biological tissues.

Inhomogeneities in the refractive index of tissue components (e.g., water, lipids, proteins), however, introduce wavefront aberrations, which compromise the image signal and resolution. These aberrations ultimately limit the imaging depth -- and hold back our understanding of many biological processes that take place within living organisms. We thus need next-generation optical tools for imaging biological tissues at depth. During her postdoc, Cristina has been working on exactly that. Through her fascination for optics, she has combined three-photon microscopy, adaptive optics, and volumetric imaging using Bessel beams, to push the boundaries of imaging depth, resolution, and speed. Cristina uses these novel optical technologies to investigate her big passion: the nervous system. She will present on the insights (literally) she has gained into the brain.
 Location:  PAIS-2540, PAIS

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