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Center for Astrophysics Research and Technologies Seminar Series Information


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Imaging Cellular Components and Dynamics with Sub-Diffraction Resolution

Friday September 22, 2017
3:30 pm

 Presenter:  Keith Lidke, UNM
 Series:  Physics and Astronomy Colloquium
 Abstract:  Due to the near transparency of cells, optical imaging is well suited for studying live or intact cells. Tagging cellular components with fluorophores dramatically extends these capabilities by providing molecular specificity and improved contrast. However, the light microscope is limited by diffraction to ~ 300 nm, whereas many important events for cell function and signaling involve interactions of proteins that occur at the ~ 10 nm scale. I will discuss using single molecule fluorescence imaging methods for circumventing the diffraction limit super-resolution and for imaging and quantifying protein dynamics and interactions in living cells. A sub-theme of the talk will be on the interesting challenges and opportunities available for the physicist working in this area. The talk will not assume any prior knowledge of biological systems.
 Host:  Gregory Taylor
 File:  http://panda3.phys.unm.edu/videos/Colloquium-170922-Lidke.mp4
 Location:  Room 125, Dane Smith Hall

Refreshments will be available before the colloquium, at 03:15 pm, in in the lobby of Dane Smith Hall.

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