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The antibiotics resistance problem and some potential solutions

Thursday March 23, 2017
5:00 pm

 Presenter:  Herman O SintimĀ 
Drug Discovery Center
Department of Chemistry, Purdue University.
 Series:  Sigma Xi Public Talk
 Abstract:  According to the US centers for disease control and prevention (CDC), antibiotic-resistant pathogens make over 2 million Americans sick every year and over 23,000 deaths per year could be attributed to these bugs. There are a few pathogens, the so-called super-bugs, that are resistant to a plethora of antibiotics. In the last decade most of the antibacterial agents that were approved by the FDA met the same antibiotic resistance fate, probably because these agents were mere derivatives of existing drugs, for which resistant bacterial strains already existed. We are currently witnessing a cyclic dinucleotide revolution that promises to usher in a new class of antibacterial agents. I will discuss some of our efforts to develop novel antibacterial agents that target bacterial communication networks, including cyclic dinucleotide signaling.
 Host:  Harjit Ahluwalia
 Location:  Room G, UNM Conference Center

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